Protein ID | Protein Name | Protein Description | Gene Name | Species | Strain | PMID |
---|---|---|---|---|---|---|
B0XPZ4 | Fe-S cluster assembly protein dre2 | Component of the cytosolic iron-sulfur (Fe-S) proteinassembly (CIA) machinery required for the maturation ofextramitochondrial Fe-S proteins. Part of an electron transfer chainfunctioning in an early step of cytosolic Fe-S biogenesis, facilitatingthe de novo assembly of a [4Fe-4S] cluster on the scaffold complexcfd1-nbp35. Electrons are transferred to dre2 from NADPH via theFAD- and FMN-containing protein tah18. Tah18-dre2 are also required forthe assembly of the diferric tyrosyl radical cofactor of ribonucleotidereductase (RNR), probably by providing electrons for reduction duringradical cofactor maturation in the catalytic small subunit rnr2 | dre2 | Aspergillus fumigatus | ku80 | 32817450 |