B0XPZ4

Protein ID Protein Name Protein Description Gene Name Species Strain PMID
B0XPZ4 Fe-S cluster assembly protein dre2 Component of the cytosolic iron-sulfur (Fe-S) proteinassembly (CIA) machinery required for the maturation ofextramitochondrial Fe-S proteins. Part of an electron transfer chainfunctioning in an early step of cytosolic Fe-S biogenesis, facilitatingthe de novo assembly of a [4Fe-4S] cluster on the scaffold complexcfd1-nbp35. Electrons are transferred to dre2 from NADPH via theFAD- and FMN-containing protein tah18. Tah18-dre2 are also required forthe assembly of the diferric tyrosyl radical cofactor of ribonucleotidereductase (RNR), probably by providing electrons for reduction duringradical cofactor maturation in the catalytic small subunit rnr2 dre2 Aspergillus fumigatus ku80 32817450