Protein ID | Protein Name | Protein Description | Gene Name | Species | Strain | PMID |
---|---|---|---|---|---|---|
B0XZA4 | Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase | Bifunctional inositol kinase that acts in concert with theIP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphategroup-containing inositol pyrophosphates diphosphoinositolpentakisphosphate, PP-InsP5, and bis-diphosphoinositoltetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, alsorespectively called InsP7 and InsP8, regulate a variety of cellularprocesses, including apoptosis, vesicle trafficking, cytoskeletaldynamics, exocytosis, insulin signaling and neutrophil activation.Phosphorylates inositol hexakisphosphate (InsP6) at positions 1 or 3 toproduce PP-InsP5 which is in turn phosphorylated by IP6Ks to produce(PP)2-InsP4. Alternatively, phosphorylates at position 1 or 3 PP-InsP5,produced by IP6Ks from InsP6, to produce (PP)2-InsP4 | AFUB_043700 | Aspergillus fumigatus | ku80 | 32817450 |