B0YD01

Protein ID Protein Name Protein Description Gene Name Species Strain PMID
B0YD01 tRNA N6-adenosine threonylcarbamoyltransferase Component of the EKC/KEOPS complex that is required for theformation of a threonylcarbamoyl group on adenosine at position 37(t(6)A37) in tRNAs that read codons beginning with adenine. The complexis probably involved in the transfer of the threonylcarbamoyl moiety ofthreonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likelyplays a direct catalytic role in this reaction, but requires otherprotein(s) of the complex to fulfill this activity. The EKC/KEOPScomplex also promotes both telomere uncapping and telomere elongation.The complex is required for efficient recruitment of transcriptionalcoactivators. KAE1 Aspergillus fumigatus ku80 32817450