C0NBR5

Protein ID Protein Name Protein Description Gene Name Species Strain PMID
C0NBR5 FACT complex subunit POB3 Component of the FACT complex, a general chromatin factorthat acts to reorganize nucleosomes. The FACT complex is involved inmultiple processes that require DNA as a template such as mRNAelongation, DNA replication and DNA repair. During transcriptionelongation the FACT complex acts as a histone chaperone that bothdestabilizes and restores nucleosomal structure. It facilitates thepassage of RNA polymerase II and transcription by promoting thedissociation of one histone H2A-H2B dimer from the nucleosome, thensubsequently promotes the reestablishment of the nucleosome followingthe passage of RNA polymerase II. HCBG_00561 Histoplasma capsulatum ATCC G217B 27303729