Protein ID | Protein Name | Protein Description | Gene Name | Species | Strain | PMID |
---|---|---|---|---|---|---|
C4YNP4 | Thiamine thiazole synthase | Involved in biosynthesis of the thiamine precursor thiazole.Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), anadenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of theprotein to a thiazole intermediate. The enzyme can only undergo asingle turnover, which suggests it is a suicide enzyme. May haveadditional roles in adaptation to various stress conditions and in DNAdamage tolerance. | THI4 | Candida albicans | strain 11 isolated from - male patient of Institute of Hematology Arthur Siqueira Cavalcanti | 25287304 |