| Protein ID | Protein Name | Protein Description | Gene Name | Species | Strain | PMID |
|---|---|---|---|---|---|---|
| J9VMR6 | Transcription and mRNA export factor SUS1 | Involved in mRNA export coupled transcription activation byassociation with both the TREX-2 and the SAGA complexes. At thepromoters, SAGA is required for recruitment of the basal transcriptionmachinery. It influences RNA polymerase II transcriptional activitythrough different activities such as TBP interaction and promoterselectivity, interaction with transcription activators, and chromatinmodification through histone acetylation and deubiquitination. Withinthe SAGA complex, participates to a subcomplex required fordeubiquitination of H2B and for the maintenance of steady-state H3methylation levels. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entranceof the nuclear pore complex (nuclear basket). TREX-2 participates inmRNA export and accurate chromatin positioning in the nucleus bytethering genes to the nuclear periphery. May also be involved incytoplasmic mRNA decay by interaction with components of P-bodies | CNAG_01396 | Cryptococcus neoformans | KN99alpha | Available only at bioRxviv |