O74189

Protein ID Protein Name Protein Description Gene Name Species Strain PMID
O74189 Dolichyl-phosphate-mannose--protein mannosyltransferase 1 Protein mannosyltransferase (PMT) involved in hyphal growthand drug sensitivity. Transfers mannose from Dol-P-mannose to Ser orThr residues on proteins. PMT1, PMT2 and PMT4 account for most of theprotein-O-glycosylation activity, while PMT5 and PMT6 may specificallymodulate a much narrower spectrum of target proteins. Accounts for theO-glycosylation of the cell wall proteins KRE9, PIR2, RHD3, and ALS1,as well as the SEC20 t-SNARE component. O-glycosylation of SEC20 isessential for its stability. Required for filamentation and earlyphases of biofilm formation. PMT1 Candida albicans modified SN152 30296253