Protein ID | Protein Name | Protein Description | Gene Name | Species | Strain | PMID |
---|---|---|---|---|---|---|
P0CY27 | Candidapepsin-1 | Secreted aspartic peptidases (SAPs) are a group of ten acidichydrolases considered as key virulence factors. These enzymes supplythe fungus with nutrient amino acids as well as are able to degrade theselected host's proteins involved in the immune defense. Induces hostinflammatory cytokine production in a proteolytic activity-independentway. Plays a role in tissue damage during superficial infection.Moreover, acts toward human hemoglobin though limited proteolysis togenerate a variety of antimicrobial hemocidins, enabling to competewith the other microorganisms of the same physiological niche using themicrobicidal peptides generated from the host protein | SAP1 | Candida albicans | strain 11 isolated from - male patient of Institute of Hematology Arthur Siqueira Cavalcanti | 25287304 |