| Protein ID | Protein Name | Protein Description | Gene Name | Species | Strain | PMID |
|---|---|---|---|---|---|---|
| Q59WK2 | Ubiquitin-related modifier 1 | Acts as a sulfur carrier required for 2-thiolation ofmcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu)and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction bybeing thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homologUBA4. The sulfur is then transferred to tRNA to form 2-thiolation ofmcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex isrequired for 2-thiolation. Also acts as a ubiquitin-like protein (UBL)that is covalently conjugated via an isopeptide bond to lysine residuesof target proteins such as AHP1. The thiocarboxylated form serves assubstrate for conjugation and oxidative stress specifically induces theformation of UBL-protein conjugates. | URM1 | Candida albicans | modified SN152 | 30296253 |