Protein ID | Protein Name | Protein Description | Gene Name | Species | Strain | PMID |
---|---|---|---|---|---|---|
Q5A1D5 | FACT complex subunit SPT16 | Component of the FACT complex, a general chromatin factorthat acts to reorganize nucleosomes. The FACT complex is involved inmultiple processes that require DNA as a template such as mRNAelongation, DNA replication and DNA repair. During transcriptionelongation the FACT complex acts as a histone chaperone that bothdestabilizes and restores nucleosomal structure. It facilitates thepassage of RNA polymerase II and transcription by promoting thedissociation of one histone H2A-H2B dimer from the nucleosome, thensubsequently promotes the reestablishment of the nucleosome followingthe passage of RNA polymerase II (By similarity). | CDC68 | Candida albicans | modified SN152 | 30296253 |