Q5AC08

Protein ID Protein Name Protein Description Gene Name Species Strain PMID
Q5AC08 Candidapepsin-6 Secreted aspartic peptidases (SAPs) are a group of ten acidichydrolases considered as key virulence factors. These enzymes supplythe fungus with nutrient amino acids as well as are able to degrade theselected host's proteins involved in the immune defense. Duringinfection, plays an important role in penetration into deeper tissuesand interaction with host defense. Activates host systemic immunity andinduces host inflammatory cytokine production in a proteolyticactivity-independent way. Contributes to corneal pathogenicity.Moreover, acts toward human hemoglobin though limited proteolysis togenerate a variety of antimicrobial hemocidins, enabling to competewith the other microorganisms of the same physiological niche using themicrobicidal peptides generated from the host protein SAP6 Candida albicans modified SN152 30296253