| Protein ID | Protein Name | Protein Description | Gene Name | Species | Strain | PMID |
|---|---|---|---|---|---|---|
| Q5AEE1 | Histone H2A.Z | Variant histone H2A which can replace H2A in somenucleosomes. Nucleosomes wrap and compact DNA into chromatin, limitingDNA accessibility to the cellular machineries which require DNA as atemplate. Histones thereby play a central role in transcriptionregulation, DNA repair, DNA replication and chromosomal stability. DNAaccessibility is regulated via a complex set of post-translationalmodifications of histones, also called histone code, and nucleosomeremodeling. This variant is enriched at promoters, it may keep them ina repressed state until the appropriate activation signal is received.Near telomeres, it may counteract gene silencing caused by the spreadof heterochromatin proteins. Required for the RNA polymerase II andSPT15/TBP recruitment to the target genes. Involved in chromosomestability (By similarity). | HTZ1 | Candida albicans | modified SN152 | 30296253 |