Q5AI15

Protein ID Protein Name Protein Description Gene Name Species Strain PMID
Q5AI15 Polyadenylate-binding protein, cytoplasmic and nuclear Binds the poly(A) tail of mRNA. Appears to be an importantmediator of the multiple roles of the poly(A) tail in mRNA biogenesis,stability and translation. In the nucleus, involved in both mRNAcleavage and polyadenylation. Is also required for efficient mRNAexport to the cytoplasm. Acts in concert with a poly(A)-specificnuclease (PAN) to affect poly(A) tail shortening, which may occurconcomitantly with either nucleocytoplasmic mRNA transport ortranslational initiation. In the cytoplasm, stimulates translationinitiation and regulates mRNA decay through translation termination-coupled poly(A) shortening, probably mediated by PAN (By similarity) PAB1 Candida albicans modified SN152 30296253